Electro-acupuncture (EA) is as effective for depression as the drug fluoxetine, according to Chinese researchers. Seventy-five patients with depressive disorder (DD) were treated with either fluoxetine or acupuncture five times per week for six weeks. EA and fluoxetine were found to have similar curative effects, but EA had a faster onset of action, better response rate and better improvement rate than fluoxetine. The researchers also looked at the effect of the two treatments on serum concentrations of glial cell line-derived neurotrophic factor (GDNF), a biomarker for damage to brain cells which is thought to play an important role in the pathogenesis of depression. Both fluoxetine and EA restored the normal concentration of GDNF in the serum of DD patients, although EA outperformed the drug in this comparison. (Effects of Electroacupuncture on Depression and the Production of Glial Cell Line-Derived Neurotrophic Factor Compared with Fluoxetine: A Randomized Controlled Pilot Study. J Altern Complement Med. September 2013, 19(9): 733-739).
Categories: Psychological / emotional